Fungi have been predicted to have been around for over a billion years. The batt
Fungi have been predicted to have been around for over a billion years. The batt
Fungi have been predicted to have been around for over a billion years. The battle between humans and fungi can be dated back to 500 BC and are one of the oldest recognised causes of infection in humans. We are constantly looking for new and innovative ways to inhibit fungal growth and prevent infection. Capsaicin, a chemical naturally found in chili species, has been heavily linked with the ability to prevent and inhibit fungal growth. In the following study, we investigated the effects of various types of capsaicin on fungi using the yeast strain ICS1 as our model. We showed that; pure capsaicin, synthetic variants of capsaicin, and naturally occurring capsaicin all had inhibitory effects on the yeast’s growth. Interestingly, we showed that the natural chilli species that did not contain any capsaicinoids also demonstrated an effect on the yeast’s growth. With further testing, it may be possible to understand the mechanism by which, capsaicinoids or other elements of the chilies, inhibit the yeast’s growth. This may then allow future treatments for fungal infections to be developed and introduced. All chemical reagents were handled suitably.

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